1 edition of Target organ toxicity: cardiovascular system found in the catalog.
Target organ toxicity: cardiovascular system
|Other titles||Target Organ Toxicity: Nervous System., Nervous system., Carviovascular system., Symposium on Target Organ Toxicity: Nervous System., Symposium on Target Organ Toxicity: Cardiovascular System.|
|Series||Environmental health perspectives -- v. 26., DHEW publication -- No. (NIH) 79-218., DHEW publication -- no. (NIH) 79-218.|
|Contributions||National Institute of Environmental Health Sciences., Society of Toxicology., Symposium on Target Organ Toxicity: Nervous System (1977 : Raleigh, N.C.), Symposium on Target Organ Toxicity: Cardiovascular System (1978 : Arlington, Va.)|
|The Physical Object|
|Pagination||[viii], 307 p. :|
|Number of Pages||307|
Causes damage to organs through prolonged or repeated exposure: Specific target organ toxicity, repeated exposure: Category 1: Danger: P, P, P P P H Causes damage to organs through prolonged or repeated exposure: Specific target organ toxicity, repeated exposure: Category 2: Warning: P P P H Very toxic to. Target organ of ethylene glycol. Target organ of streptomycin-induced toxicity. Kidney. immature immune system. Suppression of NK cell activity produces adverse effects in animals b/c. NK cells play a role in the immune surveillance of tumors and the inhibition of metastases.
Part 2: testing procedures for conventional and nontarget organ toxicities; conventional toxicity studies; carcinogenesis; mutagenesis; teratogenesis. Part 3: target organs; immunotoxicology; respiratory system - inhalation toxicology; toxicology of the liver; toxicology of the kidney; toxicology of the skin; toxicology of the eye; toxicology. We report on a functional human model to evaluate multi-organ toxicity in a 4-organ system under continuous flow conditions in a serum-free .
The new edition, which now becomes an edited work with contributions from experts around the globe, features four new chapters and a number of existing chapters that have been updated and expanded, notably those on mechanisms of toxic effects, conventional toxicity studies, the cardiovascular system, and risk assessment and regulatory toxicology. the gastrointestinal tract, kidney, liver, heart and other organs. The LD 50 in humans is approximately mg/kg, which translates into as little as mL of a 20% solution.1,2 In spite of the fact that the lung is the primary target organ, toxicity from inhalation is rare. Although pulmonary toxicity occurs later in paraquat poisoning than.
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Series: Target Organ Toxicology Target organ toxicity: cardiovascular system book (Book 25) Hardcover: pages; Publisher: CRC Press; 4 edition (September 4, ) Language: English; ISBN ; ISBN ; Product Dimensions: x x inches Shipping Weight: pounds (View shipping rates and policies) Customer Reviews: Be the first to write a review.
Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function.
New developments include:Manufacturer: CRC Press. Book Description This classic textbook now enters its forth edition, offering a distillation of decades of research and teaching experience in toxicology. Known all over the world after its translation into six languages, Lu's Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment is a benchmark text that brings clarity and insight into a rapidly evolving subject.
The book consists of four parts (Part I–Part IV) that provide guidance on principles of toxicology and testing procedures for toxicities as well as a concise, yet detailed, mechanism of both target organ and nontarget organ toxicities. The book consists of four parts (Part I-Part IV) that provide guidance on principles of toxicology and testing procedures for toxicities as well as a concise, yet detailed, mechanism of both target organ and nontarget organ : $ Target Organ Toxicity.
Dikshith. deals with specific organs of human systems that come in contact with a variety of substances in the workplace environment, or due to drug abuse and addiction, leading to the health hazards. The important organs discussed here include the skin, the respiratory system, the cardiovascular system, the.
Target Organ Toxicity, 2 • Toxicants do not affect all organs to the same extent. • A toxicant may have several sites of action and target organs.
• Multi-toxicant exposure may target the same organ. • The target organ may not be the site for storage. • Toxicokinetic processes determine concentrations in target organs.
Hughes. Specific Target Organ Toxicity – Single Exposure March Note: The specific target organ/organ system that has been primarily affected by the classified substance shall be identified, where possible, and where this is not possible, the substance shall be identified as a general toxicant.
The purpose of this document is to provide a means of classifying substances that produce specific target organ/systemic toxicity arising from repeated exposure that is not specifically addressed elsewhere in the harmonised classification system (GHS). An organ system is a structure that is found inside a human or animal.
It is made of cells or tissues that perform a specific function. When exposed to a hazardous substance, the organ that the substance affects at the lowest dose is called the target organ. Development is the process in which an individual or animal matures until puberty.
GLOBALLY HARMONIZED SYSTEM (GHS) OF CLASSIFICATION AND LABELING OF SUBSTANCES AND MIXTURES A.8 SPECIFIC TARGET ORGAN TOXICITY SINGLE EXPOSURE 1 DANGER H Causes damage to organs (state organs), (state route of exposure) 2 and the United Nations GHS Standard Purple Book.
Blood and Cardiovascular/Cardiac Toxicity results from xenobiotics acting directly on cells in circulating blood, bone marrow, and the es of blood and cardiovascular/cardiac toxicity are: Hypoxia due to carbon monoxide binding of hemoglobin preventing transport of oxygen.
Acute and Short-Term Toxicity Target organ systems of anticholinergics include the CNS, eye, cardiovascular system, respiratory system, gastrointestinal tract, genitourinary tract, and sweat glands.
These target organs differ widely depending on. Symposium on Target Organ Toxicity: cardiovascular system. The epidemiologic approach. and taking into account the effects of various risk factors known to be implicated in the etiology of cardiovascular diseases.
In spite of various methodological problems and certain inherent limitations of epidemiological studies, they can, when properly.
The cardiovascular and hematologic systems are frequent targets of toxicants. Chemical substances may produce adverse effects on the cardiovascular system by acting on the myocardial cells or the autonomic nervous system to affect the: Heart rate, Blood pressure, or.
Cardiac contractility. The target organs of toxicity are kidneys, cardiovascular system, and central nervous system. The most common side effects of BAL are hypertension with tachycardia, cardiovascular collapse, convulsions, excitation, hyperglycemia, and hypoglycemia.
The first oral contraceptive became available in and since then these sub stances, which have been used by millions of women, have probably been the most widely studied group of drugs in medical history (Drill,).
Part of the evaluation oCoral contraceptives has involved their. Continuing a long tradition, Lu‘s Basic Toxicology, Seventh Edition, combines relatively comprehensive coverage of toxic substances in food, air, and water with brevity, thereby continuing to serve as an updated introductory text for toxicology students and for those involved in allied sciences that require a background in toxicology.
The discussion of biomarkers in biological or organ systems is particularly useful for an understanding of some issues relating to key toxicity endpoints for the nervous system, cardiovascular system, respiratory system, ocular system, gastrointestinal system, skeletal system, immune system, placenta, blood and bone marrow, kidney, liver and.
Taken together, these data indicate that the vascular system is a critical target of metal toxicity and that actions of metals on the vascular system may play important roles in mediating the pathophysiologic effects of metals in specific target organs.
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Our printable books also Lu's Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment. Some books can be fully downloaded for free as pdf files, after looking for them. Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body.
Toxins do not affect all organs in the body to the same extent due to their different cell structures.
The following is a target organ categorization of effects, which may occur from exposure to hazardous chemicals, including examples of signs and symptoms, and.Symposium on Target Organ Toxicity: cardiovascular system.
The epidemiologic approach. S Pell; S Pell. Search for more papers by this author and taking into account the effects of various risk factors known to be implicated in the etiology of cardiovascular diseases. In spite of various methodological problems and certain inherent.